LabCluster
Tour "Multiplexage en Biologie spatiale "
Mardi 22 novembre 2022 • 9h00 - 12h00 |
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La participation est gratuite sur inscription Il est possible de s'inscrire à la totalité de la matinée ou seulement à une ou plusieurs conférences.Evénement organisé dans le respect des mesures sanitaires et des gestes barrières. |
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| Cliquez ici pour vous inscrire |
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Thème de la demi-journée :
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de multiplexage appliquées à l’étude de tissus |
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Programme :
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Accueil
café dès 8H30 De 9H00 à 9H40 MILTENYI BIOTEC: Ultra-high content imaging using MICS technology on the MACSima™ Imaging Platform At its core it includes the MACSima Imaging System, a fully automated instrument based on fluorescence microscopy. Its MICS (MACSimaTM Imaging Cyclic Staining) technology, together with a broad spectrum of recombinant ready-to-use antibodies, allows the analysis of hundreds of markers on a single sample, multiple samples at a time. Convenient and easy to use, its specially designed sample carriers allow you to examine any kind of fixed sample, from tissue to single cells, and the powerful and intuitive MACS iQ View Analysis Software makes for a truly game-changing imaging experience. De 9H40 à 10H20 AKOYA BIOSCIENCES: Opal and PhenoCode Signature Panels: Designed for the ever-changing combination Therapy landscape The rapidly expanding immuno-oncology therapeutic and clinical trial landscape is necessitating the need for more predictive tissue-based biomarker solutions. The PhenoCode Signature Panels provide our translational and clinical partners with a ready-made and customizable solution to rapidly advance their biomarker programs. As a powerful hybrid of Akoya’s legacy CODEX and Opal assays, the PhenoCode Signature Panels create a continuum of methodologies, enabling translational and clinical researchers to perform discovery on the PhenoCycler®-Fusion and validation on the PhenoImager platforms. As The Spatial Biology Company®, Akoya Biosciences’ mission is to bring context to the world of biology and human health through the power of spatial phenotyping. The company offers comprehensive single cell imaging solutions that allow researchers to phenotype cells with spatial context and visualize how they organize and interact to influence disease progression and response to therapy. Akoya offers a full continuum of spatial phenotyping solutions to serve the diverse needs of researchers across discovery, translational and clinical research: PhenoCode™ Panels and PhenoCycler®, PhenoImager® Fusion and PhenoImager HT Instruments. To learn more about Akoya, visit www.akoyabio.com 10H20-10H40 : PAUSE CAFÉ De 10H40 à 11H20 ULTIVUE: Profiling cancer biology using spatial phenomics Ultivue,Inc. propose des solutions complètes d’immunofluorescence multiplex pour le phénotypage tissulaire et la pathologie numérique. Grâce à la technologie InSituPlex®, vous pouvez co-localiser de 2 à 12 marqueurs pour une même lame. La chimie employée permet la préservation de l’architecture tissulaire comme de la morphologie cellulaire et rend possible le marquage H&E. Notre technologie est flexible : en effet, le marquage peut s’effectuer en manuel ou en mode automatisé sur le Leica Bond RX, et l’imagerie de la lame entière est compatible avec un vaste échantillon de scanners comme le ZEISS Axio Scan.Z1, par exemple. De 11H40 à 12H00 BIO-TECHNE: Visualize the RNA world: Multiplexing using the RNAscope® technology Visualize the expression of biomarkers and their in-situ variations at the single cell level: Applications of RNAscope® in-situ hybridization technologies RNAscope® is an innovative in-situ hybridization (ISH) technology based on Advanced Cell Diagnostics patent based on signal amplification associated with background noise suppression. This technology allows a major breakthrough for researchers by offering a simple, reliable and rapid protocol for the analysis of targets of interest on tissue sections or on cells. In a single test, RNAscope® is the only technology allowing quantitative analysis, with the maximum level of sensitivity and specificity of detection, of RNA for each constituent cell of a tissue, while maintaining observation of the morphological context. The technology therefore allows researchers to visualize which gene is expressed in which cell and to quantify its level of expression. Main Features: • Detection of one transcript copy per cell. RNAscope® probes can detect RNA that is not easily accessible or partially degraded. • Drastic increase in the signal-to-noise ratio allowing unparalleled sensitivity even for partially degraded samples. • Observation of cell-specific gene expression in an intact morphological context. • RNAscope is a technology that works on any gene in any model and on any type of tissue. • Multiplex up to 48 targets on the same sample, combine RNA and protein detection. |
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Stands de démonstration et d'information toute la matinée. Venez nous rencontrer. |
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| Le nombre de places étant limité, il est fortement conseillé de s'inscrire à l'avance en cliquant ici |
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| Pour toute question ou demande d'information, cliquez ici | |
